PLT Data is a graphical interface to create NONMEM* datasets from source files:
Source files can be from Excel (.xls, .xlsx, .csv), SAS (.xpt, .sas7bdat), or text format (pipe-delimited)
Files are converted to csv format, summarized, and a portion displayed in a text file.
Link sample / Cp data (options -- only needed if these data are in separate files).
Merge dosing and DV (Cp) data into a format accessible to NONMEM.
Time: calculate 'time after dose'; time in hours or days; referenced to first sample or dose or preceding midnight
Add covariate data (demographics / vital signs / lab values to dataset.
Calculate additional covariates (BMI, BSA, LBM, Elderly (cutoffs of 65, 70, 80 years), GFR (5 equations available).
Graphics: by subject (by period, if in dataset), time-after-dose, composites, dose-normalized
PLT Tools is a suite of tools that facilitates the conduct of NONMEM* analyses and does the following:
Run NONMEM from a graphical interface
Create high-quality graphics File NONMEM outputs automatically
Edit Control Streams without leaving PLT Tools
Model diagnostics using xpose†
Summarize runs and prepare a report (RTF format)
Create an archive of a project
Select runs to be used by the "Prepare a Report" and Archive Manager tools
* NONMEM is a registered trademark of the Regents of the University of California; NONMEM licenses are obtained from Icon Development Solutions.
† xpose copyright is held by Hooker, Karlsson, Jonsson